Why Did MediciNova Stock (MNOV) Jump Over 87% In After-Hours Trading?

Mohd Haider

October 30, 2025

MediciNova Inc. (NASDAQ:MNOV) shares surged 87.39% to $2.23 in after-hours trading on Thursday.

Check out the current price of MNOV stock here.

Publication Announcement

The California-based biopharmaceutical company said on Thursday that its research was published in the Journal of Atherosclerosis and Thrombosis, the official publication of the Japan Atherosclerosis Society and the Asian Pacific Society of Atherosclerosis and Vascular Disease.

The study, "Enhancement of ABCA1 and ABCG1 Expression and Cholesterol Efflux by a Metabolite of Tipelukast: A Potential Therapeutic Strategy for Atherosclerosis," was carried out in collaboration with a Japanese academic research group.

Research Results

According to the company, the study showed that MN-002, the primary metabolite of the oral bioavailable small molecule MN-001 (tipelukast), increased cholesterol efflux in macrophages by upregulating transport proteins ABCA1 and ABCG1.

See Also: Amazon Q3 FY2025 Earnings Call Transcript

Yuichi Iwaki, MediciNova president and CEO, said the collaborative research "provides mechanistic insight into how MN-001 and its metabolite MN-002 may influence cholesterol and lipid metabolism."

Clinical Development

Prior clinical research demonstrated that MN-001 significantly impacted patients with Type 2 diabetes and improved serum lipid profiles in patients with hypertriglyceridemia and non-alcoholic fatty liver disease (NAFLD).

The clinical-stage company is nearing completion of enrollment for a randomized, placebo-controlled, double-blind Phase 2 study in patients with hypertriglyceridemia, type 2 diabetes, and NAFLD.

Stock Performance

MediciNova reported second-quarter earnings on Aug. 14, with a loss of 7 cents per share, beating the 10-cent loss analysts expected. Revenue totaled $134,600, exceeding expectations.

The company is scheduled to report third-quarter results Nov. 12.

MediciNova's 52-week range is $1.13 to $2.55, and its market capitalization stands at $57.87 million.

The stock is down 44.13% year to date.

Price Action: According to Benzinga Pro data, MediciNova closed Thursday's regular session at $1.19, up 0.85%.

Benzinga Edge Stock Rankings indicate that MNOV has a negative price trend across all time frames. Track the performance of other players in this segment.

Read Next:

Amazon, Netflix, Apple, Reddit And Coinbase: Why These 5 Stocks Are On Investors’ Radars Today

Photo Courtesy: meeboonstudio on Shutterstock.com

Disclaimer: This content was partially produced with the help of AI tools and was reviewed and published by Benzinga editors.

Recommended

Is Elon's Empire Crumbling? - Ad

What's inside Elon's building in Memphis will shock you - Ad

November 18 Changes the Microchip Game - and Investing - Ad

Popular

Five 2026 vehicles you should absolutely wait for

Don’t buy that new car yet. If you can wait, you’ll have new 2026 model year options that aren’t out yet. Although some models barely change, others are completely redesigned and often get the latest features and improvements. Whether you’re interested in improved fuel economy, cutting-edge technology, or maybe just fresh and distinctive styling, there’s likely a car on the horizon that you’ll be interested in. To ensure you don’t miss out on the latest and greatest, the car experts at Edmunds highlight five vehicles you should consider waiting for.

Trump's $300 Million White House Ballroom Could Soon Bear A Very Familiar Name

President Donald Trump is reportedly planning to name his new $300 million White House ballroom after himself.

The 7 Red Flags Wall Street Won't Talk About

The 7 Red Flags Wall Street Won't Talk About - Ad

All 7 historic crash signals are flashing red. Once the public notices, it's too late. Our free Bellwether Signal explains how to protect wealth - and why gold and silver have been the refuge in every crisis. Don't let your retirement go over a cliff.

Warren Buffett's Berkshire Hathaway Bets Big On Consumer Brands Amid Economic Shifts

Warren Buffett and his successor Greg Abel have been directing Berkshire Hathaway towards consumer-centric investments throughout 2025.

Jim Cramer Warns 'Don't Be Fooled' Because Speculators In Gold, Quantum And Nuclear Energy Aren't Going Down 'Without A Fight'

Former hedge fund manager and renowned CNBC TV host Jim Cramer is sounding the alarm on certain speculative pockets of the market, urging investors to sell into the "snapback" momentum if they haven't already done so.

Elon's New Device Could Launch Biggest IPO of the Decade

Elon's New Device Could Launch Biggest IPO of the Decade - Ad

Elon Musk's new device is being called a "game-changer"-and even the White House is using this tech. Jeff Brown says it could launch Musk's next trillion-dollar company and make early investors rich. You can claim a stake now for as little as $500.

2026 COLA Increase: Social Security Benefits To Rise By 2.8% In 2026, Here's How Much More You Will Get Every Month

The Social Security Administration announced a 2.8% COLA increase for 2026, affecting 75 million Americans.

Trump says a Canadian ad misstated Ronald Reagan's views on tariffs. Here are the facts and context

WASHINGTON (AP) — President Donald Trump pulled out of trade talks with Canada Thursday night, furious over what he called a “fake’’ television ad from Ontario’s provincial government that quoted former U.S. President Ronald Reagan from 38 years ago criticizing tariffs -- Trump’s favorite economic tool.

The Tesla Shock Nobody Sees Coming

The Tesla Shock Nobody Sees Coming - Ad

While headlines scream "Tesla is doomed"...Jeff Brown has uncovered a revolutionary AI breakthrough buried inside Tesla's labs. One that is helping AI escape from our computer screens and manifest itself here in the real world all while creating a 25,000% growth market explosion starting as early as January 29.

Eli Lilly's Oral Weight Loss Drug Shows Superiority Over Two Approved Drugs

Orforglipron meets key endpoints in Phase 3 trials, showing A1C reduction, weight loss, and cardiovascular benefits for type 2 diabetes.

Nvidia, TSMC Unveil The First US-Made Blackwell Wafer, But Analyst Ming-Chi Kuo Flags This Overlooked Detail

Nvidia Corp (NASDAQ: NVDA) has introduced the first U.S.-made Blackwell wafer, a crucial component for AI chips, at Taiwan Semiconductor Manufacturing Co's (NYSE: TSM) facility in Phoenix.

Elon's $25 Trillion Confession

Elon's $25 Trillion Confession - Ad

Elon Musk: "Tesla will become a $25 trillion company." That would make Tesla 8x bigger than Apple today. How is that possible? He admits it's all thanks to this one AI breakthrough that will take AI out of our computer screens and manifest a 250x boom here in the real world.

China May Have Made A Breakthrough With Solid State Batteries Offering 600-Mile+ Range, Here's What You Should Know

Chinese researchers' share breakthrough in EV battery technology with solid-state batteries offering 600+ mile range and weighing 220 lbs.

The stock market is breaking records. Time for a gut check

NEW YORK (AP) — Almost everything in your 401(k) should be coming up a winner now. That makes it time for a gut check.

On November 18, a powerful new law signed by President Trump will trigger a radical shift in America's money system...

On November 18, a powerful new law signed by President Trump will trigger a radical shift in America's money system... - Ad

When a small group of private companies - not the Fed - will perform a major mint of a new kind of money. And those who act before this new system fully kicks in could see gains as high as 40X by 2032. But those who fail to prepare will be blindsided by this sea change to the U.S. dollar.

Walmart, Nova Minerals, Astera Labs, Trilogy Metals And Stellantis: Why These 5 Stocks Are On Investors' Radars Today

WMT, NVA, ALAB, TMQ, STLA were among the top trending stocks on Tuesday, Oct. 14, 2025.

Why Is BTQ Technologies Stock Up Today?

Shares of BTQ Technologies Corp. (NASDAQ:BTQ) are rising Thursday after the company announced that it reached a significant technological milestone.

November 18: D-Day For The Dollar

November 18: D-Day For The Dollar - Ad

A quiet shift in U.S. law has just authorized private companies to mint a new form of government-authorized money called the "Dollar 2.0"... and the next major mint hits on November 18. Investors who make the right moves before then could make up to 40X by 2032...

Why Did Dragonfly Energy Shares Jump Over 6% After Hours?

Dragonfly Energy Holdings' stock climbed 6.73% after hours to $1.42 following its public offering and strategic updates.

Maye Musk Says She Only 'Lasted' Until 11 PM At Elon's Saturday Meetings, Agrees With Trump's AI Czar No One Works Harder Than Her Son

Maye Musk shares insights into Elon Musk's work habits, emphasizing his dedication. She could only last until 11 PM in his Saturday meetings.

"Tech Prophet" Who Predicted the iPhone Now Predicts...

"Tech Prophet" Who Predicted the iPhone Now Predicts... - Ad

George Gilder - who predicted the iPhone 17 years early and gave Reagan the first microchip - is making his boldest call yet. He says an American nanotech "super-convergence" could mint more millionaires than any event in recent memory. He's found 3 stocks set to benefit before November 18's bombshell.

Stock Market Today: S&P 500, Nasdaq, Dow Jones Futures Rise— Micron, Bitmine, Coinbase In Focus

U.S. stock futures rose on Monday following Friday’s advances. Futures of major benchmark indices were higher.

Magnolia Oil & Gas Gets Upgrade On Strong Finances, Brighter Oil Outlook

KeyBanc raised Magnolia Oil & Gas to Overweight with a $29 target, citing a defensive profile and disciplined growth outlook.

Is Elon's Empire Crumbling?

Is Elon's Empire Crumbling? - Ad

Jeff Brown - the legend who called Tesla and Nvidia early - says Elon is about to launch a $25T AI revolution. This isn't another chatbot. It's real-world AI that could 14X the impact of ChatGPT. But after January 29, it may be too late.

Rigetti, MP Materials, And STMicroelectronics Are Among Top 10 Large Cap Losers Last Week (Oct. 20-Oct. 24): Are the Others in Your Portfolio?

Large-cap losers last week included RGTI, STM, QBTS, SMR, DECK, HMY, MP, ASTS, OKLO, FRMI amid guidance misses, downgrades headwinds.

Trump Administration Explores Possible Meeting With Kim Jong Un During Asia Trip

Trump considers meeting Kim Jong Un during upcoming Asia trip, but no concrete plans have been made amid ongoing China trade negotiations.

What's inside Elon's building in Memphis will shock you

What's inside Elon's building in Memphis will shock you - Ad

Inside Elon Musk's Memphis site lies a supercomputer built to power the world's first superhuman AI. It could make Elon a trillionaire - and new millionaires, too. With just $500, you could get in before the December 1st funding window closes.

Japan's exports and imports grow in September despite Trump's tariffs

TOKYO (AP) — Japan’s exports grew 4.2% in September, according to government data Wednesday, on robust shipments to Asia that offset a decline in exports to the U.S., which were impacted by President Donald Trump’s tariffs.

Nvidia's New Partner And Rival: Intel, AMD Witness Improving Technical Indicators Amid Solid Momentum Gains

Nvidia's new partner, Intel, and rival AMD show strong momentum gains, reshaping the semiconductor landscape.

November 18 Changes the Microchip Game - and Investing

November 18 Changes the Microchip Game - and Investing - Ad

George Gilder-dubbed "America's #1 Futurist"-says while everyone's chasing AI, the real opportunity is in a 4-nanometer tech millions of times more complex. It's not another chip - it replaces them. Now built in Arizona, Gilder says 3 companies tied to this "super-convergence" could soar.

AP Business News Digest

Here are the AP's top business stories that have moved or are planned to move today. All times U.S. Eastern. For up-to-the minute information on AP's coverage, visit AP Newsroom’s .

Australian Oilseeds Holdings Shares Soar 248% After Hours Amid Trump Says US Will Make Its Own Cooking Oil

Australian Oilseeds Holdings surged 248% after Trump's trade threat against China sparked a rally in agricultural biotech stocks.

The 7 Red Flags Wall Street Won't Talk About

The 7 Red Flags Wall Street Won't Talk About - Ad

Trump's immigration crackdown weighs heavy on the US labor market

Maria worked cleaning schools in Florida for $13 an hour. Every two weeks, she’d get a $900 paycheck from her employer, a contractor. Not much — but enough to cover rent in the house that she and her 11-year-old son share with five families, plus electricity, a cellphone and groceries.

Tesla, Palantir JPMorgan And More — Here's Why Investors Couldn't Stop Talking About These Stocks This Week

Retail investors buzzed about five stocks this week, from Oct. 13 to Oct. 17 on X and Reddit's r/WallStreetBets: TSLA, RGTI, OKLO, JPM, PLTR

Elon's New Device Could Launch Biggest IPO of the Decade

Elon's New Device Could Launch Biggest IPO of the Decade - Ad

Elon Musk Claps Back At Hefty Pay Critics: 'Which Of Those CEOs Would You Like To Run Tesla?' — Company Worth More Than All Other Automakers Combined

Elon Musk defends his position as Tesla CEO amid ISS opposition to his trillion-dollar pay package set for voting next month.

Edmunds compares the new BMW X3 and Mercedes-Benz GLC

Compact luxury crossovers are ideal if you’re seeking a compelling blend of utility and style without having to pay full-size luxury SUV pricing. The has been a front-runner since the original model’s introduction in 2003, but it continues to face stiff competition from the .

The Tesla Shock Nobody Sees Coming

The Tesla Shock Nobody Sees Coming - Ad

Why Is Trump Memecoin Soaring As Bitcoin, Ethereum Tumble?

The Official Trump (CRYPTO: TRUMP) memecoin erupted into a double-digit rally on Wednesday amid reports that the project's issuer is in talks to buy crowdfunding platform Republic.

Trending Now