Rare Disease Biotech Offers Access Ahead of Key Milestone

This late-stage biotech is gearing up for Phase 2 trials with an FDA-designated orphan drug. It's already drawing comparisons to recent billion-dollar exits. Backed by a proven biotech incubator, it's now offering early access to its raise.

Benzinga Bulls And Bears: Oracle, Costco, NIO — And Wall Street Snaps Its Slide

Benzinga Senior Editor
September 27, 2025

Benzinga examined the prospects for many investors' favorite stocks over the last week -- here's a look at some of our top stories.

Wall Street snapped a three-day slide as inflation data aligned with expectations, easing fears of aggressive Fed moves. The S&P 500 gained ~0.6%, the Dow added ~299 points, and the Nasdaq rose ~0.4%, with all three indexes pushing toward earlier highs.

U.S. GDP growth surprised to the upside -- final Q2 came in at 3.8%, while August PCE inflation edged up to 2.7% year-over-year, and core PCE held at 2.9%. Gold soared past $3,800/oz, up ~43% year-to-date, while silver rallied ~15% for the month.

Despite the rebound, questions loom over Fed strategy. Federal Reserve Chair Jerome Powell reiterated there's "no preset path," reflecting tension between sticky inflation and signs of labor market cooling. Markets now look ahead to PCE, employment, and how the Fed navigates growing expectations for further easing.

Benzinga provides daily reports on the stocks most popular with investors. Here are a few of this past week's most bullish and bearish posts that are worth another look.

The Bulls

"Oracle stock rises after Trump signs executive order on TikTok", by Adam Eckert, reports that Oracle Corp. (NYSE: ORCL) shares jumped in extended trading after President Donald Trump issued an executive order approving a deal to keep TikTok operating in the U.S., naming Oracle to manage TikTok's U.S. security operations and provide cloud services.

"UniQure stock's 248% blastoff was just the start -- ask Wall Street", by Surbhi Jain, reports that UniQure NV (NASDAQ: QURE) rallied 248% in one session after announcing promising trial results for its experimental Huntington's disease gene therapy, prompting analysts at Stifel and Leerink to raise price targets to $65 and $68 and signaling renewed optimism about the stock's long-term upside.

"Costco beats Q4 earnings, revenue estimates as comparable sales climb 5.7%", by Adam Eckert, reports that Costco Wholesale Corp. (NASDAQ: COST) delivered $86.16 billion in revenue -- beating estimates -- and $5.87 in adjusted EPS, while same-store sales rose 5.7% year-over-year and membership fees jumped to $1.72 billion.

For additional bullish calls of the past week, check out the following:

Oklo, NuScale, Nano Nuclear Stocks Soar -- The $10 Trillion Nuclear Bet Is On

Snap Stock Goes Full Meme -- Buyout Rumors Meet Retail's Roar

The Bears

"Bitcoin, Ethereum, XRP plunge taking crypto-linked stocks down", by Erica Kollmann, reports that Bitcoin (CRYPTO: BTC) dropped below $110,000, Ethereum (CRYPTO: ETH) slid under $3,900, and XRP (CRYPTO: XRP) dipped below $2.75 -- pressuring crypto-tied equities like Riot Platforms Inc. (NASDAQ: RIOT), MARA Holdings Inc. (NASDAQ: MARA), HIVE Digital Technologies Inc. (NASDAQ: HIVE), Coinbase Global Inc. (NASDAQ: COIN) and Strategy Inc. (NASDAQ: MSTR), all of which fell sharply amid the broader selloff.

"NIO and Li Auto fall as Beijing tightens grip on EV exports", by Anusuya Lahiri, reports that NIO Inc. (NYSE: NIO) and Li Auto Inc. (NASDAQ: LI) tumbled after Beijing announced that starting Jan. 1, 2026, automakers will need new export permits to ship electric vehicles abroad -- part of a broader effort to curb industry discounting and stabilize the domestic EV sector.

"What Freeport's mud rush disaster means for its stock", by Triveni Kothapalli, reports that after a deadly mud rush at its Grasberg mine in Indonesia, Freeport-McMoRan Inc. (NYSE: FCX) was downgraded by Scotiabank from Sector Outperform to Sector Perform, with its 12-month target cut to $45 from $55, on expectations of significantly deferred production -- especially a 35% drop in 2026 output -- and steep cuts to 2025–26 earnings, EBITDA, and free cash flow.

For more bearish takes, be sure to see these posts:

CarMax Stock Hits 52-Week Low After Q2 Earnings – Here's Why

Freeport-McMoRan Confronts Hard Questions After Fatal Mud Rush In Indonesia

Transocean (RIG) Stock Is Diving After Hours: Here's Why

Keep up with all the latest breaking news and trading ideas by following Benzinga on X.

Image created using artificial intelligence via Midjourney.

Continue Reading...

Popular

MP Materials Tops List For Rare Earth Exposure, Says Analyst

Rare earth stocks are gaining attention as demand for magnets in EVs, robotics, and advanced air mobility is set to double by 2035.

Tesla Set To Hit $3 Trillion in 2026—Dan Ives

Tesla bull and Wedbush tech analyst Dan Ives sees Tesla reaching a $1 trillion valuation before the end of 2026. 

The "Mar-A-Lago Accord" Is Now Underway - Ad

The global order is in chaos. And according to 40-year market veteran Dr. David Eifrig, the biggest controlled demolition of the old monetary order in history could now be here, too. That means if you don't take action today, your wealth could decline by 40%... (Yes, even your cash savings.)

Web of business interests shows that Kimmel's future rests on far more than his jokes

NEW YORK (AP) — The decision about whether to keep on his late-night ABC show depends on far more than his jokes. The choice is complicated by a web of business and regulatory considerations involving ABC’s parent company, other media companies and the Trump administration.

Time to Say Goodbye to "Old" Dollar? Say Hello to "Trump's New Dollar" - Ad

If you have any money in U.S. dollars... learn how to prepare for "Trump's new dollar"... Because this could be the biggest change to our financial system in 54 years. President Trump even called it: "The greatest revolution in financial technology since the birth of the internet itself."

Ex-Trump Lawyer Raises Alarms: 'I Have Never Been As Concerned As To Whether Our System Can Withstand The Pressure'

Abbe Lowell, a lawyer who once represented President Donald Trump's family, has expressed grave concerns over the potential harm the current administration could cause to the country's institutions.

Cathie Wood Loads Up On Bullish Inc, Pony AI And Robinhood — Dumps Kratos Defense Amid Taiwan Drone Buzz

On Sept 17, 2025, Cathie Wood-led Ark Invest executed significant trades involving Bullish, Kratos Defense, Pony AI, and Robinhood. These reflect Ark's focus on emerging tech and defense sectors.

New Biotech Offering Targets $426B Rare Disease Market - Ad

The rare disease drug space is growing fast-and so is investor interest. With exclusivity, pricing power and major M&A moves, the rare disease space is getting interesting. This company has the science and the experience.

Fed convenes meeting with a governor newly appointed by Trump and another he wants to oust

WASHINGTON (AP) — After a and the Federal Reserve began a key meeting on interest rate policy Tuesday with both a new Trump administration appointee and an official the White House has targeted for removal.

New York City's Wealthiest Neighborhoods Witness 60% Rent Surge Since Pandemic

House rental rates in some of the wealthiest neighborhoods of New York City have surged by over 60% since the COVID-19 pandemic began, putting even high-income earners in a tight spot.

Biotech With Multiple Orphan Drugs Is Quietly Opening Its Doors - Ad

A promising biotech developing treatments for rare childhood brain diseases is opening a new raise. Its lead drug has fast-track status, orphan designations, is nearing Phase 2 and backed by a Global Integrator.

BlackRock Turns Popular Mutual Funds Into Global Equity ETFs

BlackRock turns two top mutual funds into active ETFs, giving investors global equity exposure and strategies to manage volatility.

[Revealed] Trump's Next AI Executive Orders? - Ad

A White House insider with direct ties to Trump's inner circle just revealed what he calls "Manhattan II" - a potential $2.2 trillion AI initiative set to launch as soon as Oct 15. He says this could mirror past U.S. projects that minted fortunes - with small firms soaring 5,000% to 10,000% over two decades. And now he's giving away his #1 stock pick for free before the deadline.

Big Tech's energy-hungry data centers could be bumped off grids during power emergencies

HARRISBURG, Pa. (AP) — With the explosive growth of Big Tech's data centers threatening to overload U.S. electricity grids, policymakers are taking a hard look at a tough-love solution: bumping the energy-hungry data centers off grids during power emergencies.

Nvidia Is About to Shock the World: October 23rd - Ad

Jeff Brown, the tech legend who picked shares of Nvidia in 2016 before they jumped by more than 22,000%, is warning everyone to... Mark this date on your calendar: October 23rd! That's when Nvidia could help send shares of this Elon Musk supplier skyrocketing higher.

US jobless aid applications retreat to 231,000 after surging to nearly 4-year high a week earlier

The number of Americans applying for jobless aid last week retreated significantly after surging to a nearly four-year high a week earlier.

The Tesla Shock Nobody Sees Coming - Ad

While headlines scream "Tesla is doomed"...Jeff Brown has uncovered a revolutionary AI breakthrough buried inside Tesla's labs. One that is helping AI escape from our computer screens and manifest itself here in the real world all while creating a 25,000% growth market explosion starting as early as October 23rd.

Elizabeth Warren Says Measles Can Hit Record Highs, Slams RFK Jr.'s CDC Panel For Delaying Vaccine: 'How Does That Keep Our Kids Safe?'

Sen. Elizabeth Warren (D-Mass.) on Thursday criticized the Centers for Disease Control and Prevention's vaccine advisory panel following its controversial vote to delay the combined measles, mumps, rubella, and varicella or MMRV vaccine for children under 4 years old.

Charlie Kirk Raised $85 Million Last Year — Widow Vows to Continue His Work

The assassination of Turning Point USA founder Charlie Kirk at a Utah Valley University event on September 10 has cast a shadow of uncertainty over the future of his political and business ventures.

Elon's $25 Trillion Confession - Ad

Elon Musk: "Tesla will become a $25 trillion company." That would make Tesla 8x bigger than Apple today. How is that possible? He admits it's all thanks to this one AI breakthrough that will take AI out of our computer screens and manifest a 250x boom here in the real world.

Warsaw turns to Ukraine for drone warfare expertise after Russian drones enter Polish airspace

KYIV, Ukraine (AP) — Poland’s defense chief traveled to Kyiv on Thursday in search of Ukrainian help in developing his country's drone warfare capabilities, just over a week after and exposed to drone warfare.

New England's shrimp industry is struggling, with fishermen catching few in 2025

PORTLAND, Maine (AP) — There's an effort underway to bring New England shrimp back to seafood customers — but fishermen have found few of the crustaceans, and the fishing industry that harvests them may face an even longer shutdown.

Crypto Meets Wall Street - Are You Ready? - Ad

The Hedge Fund Summit is bringing top minds from crypto and traditional finance together. Discover new strategies, insights, and connections that could shape your portfolio's future.

AI Bull Market Fuels A Wave Of New Listings: 3 IPO ETFs In Focus

IPO-ETFs like IPO, FPX and FPXI are in focus as the U.S. market sees its fastest rebound since 2021, fueled by the AI boom and $23B raised year-to-date.

FDA proposes ban on Orange B, a food dye not used for decades

Federal regulators are proposing to remove another from the U.S. food supply — Orange B, a synthetic color that hasn't been used in the U.S. for decades.

Rare Disease Biotech Offers Access Ahead of Key Milestone - Ad

This late-stage biotech is gearing up for Phase 2 trials with an FDA-designated orphan drug. It's already drawing comparisons to recent billion-dollar exits. Backed by a proven biotech incubator, it's now offering early access to its raise.

Co-Diagnostics Stock Plunges 28% In Pre-Market Despite Strategic Saudi Partnership

Co-Diagnostics (CODX) shares dropped 24.87% in pre-market trading after an 80.76% surge, despite announcing a strategic partnership.

The "Mar-A-Lago Accord" Is Now Underway - Ad

The global order is in chaos. And according to 40-year market veteran Dr. David Eifrig, the biggest controlled demolition of the old monetary order in history could now be here, too. That means if you don't take action today, your wealth could decline by 40%... (Yes, even your cash savings.)

Labor Dispute Eases As UAW, GE Aerospace Agree On Tentative Pact

UAW members at GE Aerospace plants in Ohio and Kentucky reached a tentative deal, with a ratification vote set for Sept. 19.

Long-wrought WTO agreement aimed at reducing overfishing takes effect

GENEVA (AP) — A World Trade Organization agreement aimed at reducing took effect Monday, requiring countries to reduce subsidies doled out to fishing fleets and aiming to ensure sustainability of wildlife in the world's seas and oceans.

Time to Say Goodbye to "Old" Dollar? Say Hello to "Trump's New Dollar" - Ad

If you have any money in U.S. dollars... learn how to prepare for "Trump's new dollar"... Because this could be the biggest change to our financial system in 54 years. President Trump even called it: "The greatest revolution in financial technology since the birth of the internet itself."

Trump Admin Pushes G7, EU To Slap Tariffs On China And India Over Russian Oil Purchase To 'End The Senseless Killing' In Ukraine

The U.S. is pressing G7 and EU allies to impose tariffs on China and India for buying Russian oil, while Trump's trade war policies have driven tariff revenues to a record $30 billion in August.

SciSparc Stock Shoots Up Over 89% After Hours: What's Going On?

SciSparc's stock surged 89.13% to $3.48 after-hours on news of a court-granted stay in its merger with AutoMax, though the stock remains down 71.87% over the past year.

New Biotech Offering Targets $426B Rare Disease Market - Ad

The rare disease drug space is growing fast-and so is investor interest. With exclusivity, pricing power and major M&A moves, the rare disease space is getting interesting. This company has the science and the experience.

US To Set $5 Billion Critical Minerals Fund

US to launch $5 billion fund for critical minerals, in partnership with Orion Resource Partners and other investors. Aimed at reducing reliance on Chinese supply chains and securing long-term resources.

Trending Now

Information, charts or examples are for illustration and educational purposes only and not for individualized investment management This message contains commercial elements, such as advertising. We only send these offers to those who have opted in to our newsletter. Past performance is not indicative of future results. For these reasons we strongly suggest trading in a DEMO/Simulated account. The information provided by us is for educational and informational purposes only. We make no representations or warranties concerning the products, practices or procedures of any company or entity mentioned or recommended and have not determined if the statements and opinions of the advertiser are accurate, correct or truthful. If you use, act upon or make decisions in reliance on information contained or any external source linked within it, you do so at your own peril and agree to hold us, our officers, directors, shareholders, affiliates and agents without fault.

Copyright smartmoneytrading.net
Privacy Policy | Terms of Service